Targets / Kinase / AURKC

aurora kinase C (AURKC)

Target Class
Kinase
Family
Other
Official Symbol
AURKC
Entrez Gene ID
6795
Species
Human
Accession Number
AAC77369.1
Alias Names
AIE2; AIK3; ARK-3; ARK3; AurC; SPGF5; STK13; aurora 3; aurora kinase C; aurora-C; aurora-related kinase 3; aurora/IPL1-related kinase 3; aurora/IPL1/EG2 protein 2; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine-protein kinase 13; serine/threonine-protein kinase aurora-C
Background
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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