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AKT serine/threonine kinase 3 (AKT3)

Target Class
Kinase
Family
AGC
Official Symbol
AKT3
Entrez Gene ID
10000
Species
Human
Accession Number
NP_005456.1
Alias Names
PKB gamma; PKB-GAMMA; PKBG; PRKBG; RAC-PK-gamma; RAC-gamma; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; STK-2; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Background
The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
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Related Group Members: AGC
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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