activin A receptor type II-like 1 (ACVRL1)

Target Class
Official Symbol
Entrez Gene ID
Accession Number
Alias Names
ACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TGF-B superfamily receptor type I; TSR-I; activin A receptor type II-like 1; activin A receptor, type II-like kinase 1; activin receptor-like kinase 1; serine/threonine-protein kinase receptor R3
This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members: TKL

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Assay Measures Background Species Cell Line
ACVRL1/ACVR2 Dimerization U2OS Human 93-0963C3
ACVRL1/ACVR2B Dimerization U2OS Human 93-0964C3
ACVRL1/BMPR2 Dimerization U2OS Human 93-0962C3
Assay Measures Background Species Assay Kit
ACVRL1/BMPR2 Dimerization U2OS Human 93-0962E3CP22M
ACVRL1/BMPR2 Dimerization U2OS Human 93-0962E3CP22L
ACVRL1/ACVR2 Dimerization U2OS Human 93-0963E3CP0M
ACVRL1/ACVR2 Dimerization U2OS Human 93-0963E3CP0L
ACVRL1/ACVR2B Dimerization U2OS Human 93-0964E3CP22M
ACVRL1/ACVR2B Dimerization U2OS Human 93-0964E3CP22L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan