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Vasoactive intestinal peptide receptor 1 (VPAC1)

Target Class
GPCR
Family
VIP and PACAP
Official Symbol
VIPR1
Species
Human
Accession Number
NM_004624
Alias Names
HVR1; II; PACAP type II receptor; PACAP-R-2; PACAP-R2; RDC1; V1RG; VAPC1; VIP and PACAP receptor 1; VIP receptor, type I; VIP-R-1; VIPR; VIRG; VPAC1; VPAC1R; VPCAP1R; pituitary adenylate cyclase activating polypeptide receptor, type II; vasoactive intestinal peptide receptor 1; vasoactive intestinal polypeptide receptor 1
Background
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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Solution Portfolio

Related Family Members:

VIP and PACAP
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0316C2
Internalization U2OS Human 93-0739C3
cAMP CHO-K1 Human 95-0093C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0093E2CP2S
cAMP CHO-K1 Human 95-0093E2CP2M
cAMP CHO-K1 Human 95-0093E2CP2L
β-Arrestin CHO-K1 Human 93-0316E2CP0S
β-Arrestin CHO-K1 Human 93-0316E2CP0M
β-Arrestin CHO-K1 Human 93-0316E2CP0L
Internalization U2OS Human 93-0739E3CP5S
Internalization U2OS Human 93-0739E3CP5M
Internalization U2OS Human 93-0739E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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