Vasoactive intestinal peptide receptor 1 (VPAC1)
- Target Class
- GPCR
- Family
- VIP and PACAP
- Official Symbol
- VIPR1
- Species
- Human
- Accession Number
- NM_004624
- Alias Names
- HVR1; II; PACAP type II receptor; PACAP-R-2; PACAP-R2; RDC1; V1RG; VAPC1; VIP and PACAP receptor 1; VIP receptor, type I; VIP-R-1; VIPR; VIRG; VPAC1; VPAC1R; VPCAP1R; pituitary adenylate cyclase activating polypeptide receptor, type II; vasoactive intestinal peptide receptor 1; vasoactive intestinal polypeptide receptor 1
- Background
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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Solution Portfolio
Related Family Members:
VIP and PACAP
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| cAMP |
CHO-K1 |
Human |
95-0093C2 |
| β-Arrestin |
CHO-K1 |
Human |
93-0316C2 |
| Internalization |
U2OS |
Human |
93-0739C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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