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Prostaglandin F receptor (FP) (FP)

Target Class
GPCR
Family
Prostanoid
Official Symbol
PTGFR
Species
Human
Accession Number
NM_000959.3
Alias Names
FP; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor
Background
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Prostanoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
Internalization U2OS Human 93-0872C3
Calcium CHO-K1 Human 95-1009C2
β-Arrestin U2OS Human 93-0936C3
Assay Readout Background Species Assay Kit
Internalization U2OS Human 93-0872E3CP0S
Internalization U2OS Human 93-0872E3CP0M
Internalization U2OS Human 93-0872E3CP0L
β-Arrestin U2OS Human 93-0936E3CP5S
β-Arrestin U2OS Human 93-0936E3CP5M
β-Arrestin U2OS Human 93-0936E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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