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Melatonin receptor 1B (MT2)

Target Class
GPCR
Family
Melatonin
Official Symbol
MTNR1B
Species
Human
Accession Number
NM_005959.3
Alias Names
FGQTL2; MEL-1B-R; MT2; mel1b receptor; melatonin receptor 1B; melatonin receptor MEL1B; melatonin receptor type 1B
Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Melatonin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout ▲BackgroundSpeciesCell Line
cAMPCHO-K1Human95-0056C2
InternalizationU2OSHuman93-0881C3
β-ArrestinCHO-K1Human93-0630C2
 
Assay Readout ▲BackgroundSpeciesAssay Kit
cAMPCHO-K1Human95-0056E2CP2S
cAMPCHO-K1Human95-0056E2CP2M
cAMPCHO-K1Human95-0056E2CP2L
β-ArrestinCHO-K1Human93-0630E2CP0S
β-ArrestinCHO-K1Human93-0630E2CP0M
β-ArrestinCHO-K1Human93-0630E2CP0L
 
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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