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Melatonin receptor 1B (MT2)

Target Class
GPCR
Family
Melatonin
Official Symbol
MTNR1B
Species
Human
Accession Number
NM_005959.3
Alias Names
FGQTL2; MEL-1B-R; MT2; mel1b receptor; melatonin receptor 1B; melatonin receptor MEL1B; melatonin receptor type 1B
Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Melatonin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0630C2
Internalization U2OS Human 93-0881C3
cAMP CHO-K1 Human 95-0056C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0056E2CP2S
cAMP CHO-K1 Human 95-0056E2CP2M
cAMP CHO-K1 Human 95-0056E2CP2L
β-Arrestin CHO-K1 Human 93-0630E2CP0S
β-Arrestin CHO-K1 Human 93-0630E2CP0M
β-Arrestin CHO-K1 Human 93-0630E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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