Melatonin receptor 1B (MT2)
- Target Class
- GPCR
- Family
- Melatonin
- Official Symbol
- MTNR1B
- Species
- Human
- Accession Number
- NM_005959.3
- Alias Names
- FGQTL2; MEL-1B-R; MT2; mel1b receptor; melatonin receptor 1B; melatonin receptor MEL1B; melatonin receptor type 1B
- Background
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Melatonin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0630C2 |
| Internalization |
U2OS |
Human |
93-0881C3 |
| cAMP |
CHO-K1 |
Human |
95-0056C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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