MAS-related GPR, member D (MRGPRD)
- Target Class
- GPCR
- Family
- Class A Orphan
- Official Symbol
- MRGPRD
- Species
- Human
- Accession Number
- NM_198923
- Alias Names
- G-protein coupled receptor TGR7; MAS-related GPR, member D; MRGD; TGR7; beta-alanine receptor; mas-related G protein-coupled MRGD; mas-related G-protein coupled receptor member D
- Background
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
+ Show More
Solution Portfolio
Related Family Members:
Class A Orphan
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
|
Chem-1 |
Human |
HTS206C |
| β-Arrestin |
CHO-K1 |
Human |
93-0926C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
|
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms