MAS-related GPR, member D (MRGPRD)

Target Class
Class A Orphan
Official Symbol
Accession Number
Alias Names
G-protein coupled receptor TGR7; MAS-related GPR, member D; MRGD; TGR7; beta-alanine receptor; mas-related G protein-coupled MRGD; mas-related G-protein coupled receptor member D
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin- stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
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Solution Portfolio

Related Family Members:

Class A Orphan

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
Chem-1 Human HTS206C
β-Arrestin CHO-K1 Human 93-0926C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0926E2CP2M
β-Arrestin CHO-K1 Human 93-0926E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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