Histamine receptor H4 (H4)
- Target Class
- GPCR
- Family
- Histamine
- Official Symbol
- HRH4
- Species
- Human
- Accession Number
- NM_021624
- Alias Names
- AXOR35; BG26; G-protein coupled receptor 105; GPCR105; GPRv53; H4; H4R; HH4R; SP9144; histamine H4 receptor; histamine receptor H4; pfi-013
- Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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Solution Portfolio
Related Family Members:
Histamine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
U2OS |
Human |
93-0209C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
|
|
|
Available |
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