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Histamine receptor H4 (H4)

Target Class
Official Symbol
Accession Number
Alias Names
AXOR35; BG26; G-protein coupled receptor 105; GPCR105; GPRv53; H4; H4R; HH4R; SP9144; histamine H4 receptor; histamine receptor H4; pfi-013
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
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Solution Portfolio

Related Family Members:


DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
β-Arrestin U2OS Human 93-0209C3
Assay Readout Background Species Assay Kit
β-Arrestin U2OS Human 93-0209E3CP0S
β-Arrestin U2OS Human 93-0209E3CP0M
β-Arrestin U2OS Human 93-0209E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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