Histamine receptor H3 (H3)

Target Class
Official Symbol
Accession Number
Alias Names
G protein-coupled receptor 97; G-protein coupled receptor 97; GPCR97; H3R; HH3R; histamine H3 receptor; histamine receptor H3
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:


DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0509C2
cAMP CHO-K1 Human 95-0103C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0103E2CP2M
cAMP CHO-K1 Human 95-0103E2CP2L
β-Arrestin CHO-K1 Human 93-0509E2CP2M
β-Arrestin CHO-K1 Human 93-0509E2CP2L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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