G-protein coupled receptor 143 (GPR143)
- Target Class
- GPCR
- Family
- Other 7TM proteins
- Official Symbol
- GPR143
- Species
- Human
- Accession Number
- NM_000273
- Alias Names
- G protein-coupled receptor 143; G-protein coupled receptor 143; NYS6; OA1; ocular albinism 1 (Nettleship-Falls); ocular albinism type 1 protein
- Background
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
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Solution Portfolio
Related Family Members:
Other 7TM proteins
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0362C2A |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
| |
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|
Available |
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