Find a Product

G-protein coupled receptor 143 (GPR143)

Target Class
GPCR
Family
Other 7TM proteins
Official Symbol
GPR143
Species
Human
Accession Number
NM_000273
Alias Names
G protein-coupled receptor 143; G-protein coupled receptor 143; NYS6; OA1; ocular albinism 1 (Nettleship-Falls); ocular albinism type 1 protein
Background
This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]
+ Show More

Solution Portfolio

Related Family Members:

Other 7TM proteins
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0362C2A
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0362E2ACP1S
β-Arrestin CHO-K1 Human 93-0362E2ACP1M
β-Arrestin CHO-K1 Human 93-0362E2ACP1L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
The DiscoveRx Advantage:
Access your Target with Three Signaling Platforms