Glucagon-like peptide receptor 2 (GLP-2)

Target Class
Official Symbol
Accession Number
Alias Names
GLP-2 receptor; GLP-2-R; GLP-2R; glucagon-like peptide 2 receptor
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq, Jul 2008]
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Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0572C2
Internalization U2OS Human 93-0750C3
cAMP CHO-K1 Human 95-0112C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0112E2CP2M
cAMP CHO-K1 Human 95-0112E2CP2L
β-Arrestin CHO-K1 Human 93-0572E2CP2M
β-Arrestin CHO-K1 Human 93-0572E2CP2L
Assay Qualified With Assay Measures Background Species Assay Kit
GLP-2 β-Arrestin CHO-K1 Human 93-0572Y2-00133
GLP-2 β-Arrestin CHO-K1 Human 93-0572Y2-00134
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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