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Coagulation factor II (thrombin) receptor-like 3 (PAR4) (PAR4)

Target Class
GPCR
Family
Protease activated
Official Symbol
F2RL3
Species
Human
Accession Number
AY431102
Alias Names
PAR-4; PAR4; coagulation factor II (thrombin) receptor-like 3; coagulation factor II receptor-like 3; protease-activated receptor-4; proteinase-activated receptor 4; proteinase-activated receptor-4; thrombin receptor-like 3
Background
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Protease activated
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
Internalization U2OS Human 93-0753C3
β-Arrestin CHO-K1 Human 93-0279C2
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0279E2CP0S
β-Arrestin CHO-K1 Human 93-0279E2CP0M
β-Arrestin CHO-K1 Human 93-0279E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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