Coagulation factor II (thrombin) receptor-like 3 (PAR4) (PAR4)
- Target Class
- GPCR
- Family
- Protease activated
- Official Symbol
- F2RL3
- Species
- Human
- Accession Number
- AY431102
- Alias Names
- PAR-4; PAR4; coagulation factor II (thrombin) receptor-like 3; coagulation factor II receptor-like 3; protease-activated receptor-4; proteinase-activated receptor 4; proteinase-activated receptor-4; thrombin receptor-like 3
- Background
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Protease activated
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| Assay Readout |
Background |
Species |
Cell Line |
| Internalization |
U2OS |
Human |
93-0753C3 |
| β-Arrestin |
CHO-K1 |
Human |
93-0279C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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