Cannabinoid receptor 2 (CB2)
- Target Class
- GPCR
- Family
- Cannabinoid
- Official Symbol
- CNR2
- Species
- Human
- Accession Number
- AY242132
- Alias Names
- CB-2; CB2; CX5; cannabinoid receptor 2; cannabinoid receptor 2 (macrophage); testis-dominant CNR2 isoform CB2
- Background
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Cannabinoid
?
DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
HEK 293 |
Human |
93-0201C1 |
| β-Arrestin |
CHO-K1 |
Human |
93-0706C2 |
| cAMP |
CHO-K1 |
Human |
95-0060C2 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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