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Cannabinoid receptor 2 (CB2)

Target Class
GPCR
Family
Cannabinoid
Official Symbol
CNR2
Species
Human
Accession Number
AY242132
Alias Names
CB-2; CB2; CX5; cannabinoid receptor 2; cannabinoid receptor 2 (macrophage); testis-dominant CNR2 isoform CB2
Background
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Cannabinoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0706C2
cAMP CHO-K1 Human 95-0183C2
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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