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Cannabinoid receptor 1 (CB1)

Target Class
GPCR
Family
Cannabinoid
Official Symbol
CNR1
Species
Human
Accession Number
AY225225
Alias Names
CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR; cannabinoid receptor 1; cannabinoid receptor 1 (brain); central cannabinoid receptor
Background
This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009]
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Solution Portfolio

Related Family Members:

Cannabinoid
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
cAMP CHO-K1 Human 95-0071C2
β-Arrestin CHO-K1 Human 93-0959C2
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0071E2CP2S
cAMP CHO-K1 Human 95-0071E2CP2M
cAMP CHO-K1 Human 95-0071E2CP2L
β-Arrestin CHO-K1 Human 93-0959E2CP0S
β-Arrestin CHO-K1 Human 93-0959E2CP0M
β-Arrestin CHO-K1 Human 93-0959E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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