Cholinergic receptor, muscarinic 3 (M3)
- Target Class
- GPCR
- Family
- Acetylcholine
- Official Symbol
- CHRM3
- Species
- Human
- Accession Number
- AF498917
- Alias Names
- EGBRS; HM3; acetylcholine receptor, muscarinic 3; cholinergic receptor, muscarinic 3; m3 muscarinic receptor; muscarinic acetylcholine receptor M3
- Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Acetylcholine
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| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
U2OS |
Human |
93-0860C3 |
| Internalization |
U2OS |
Human |
93-0775C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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