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Cholinergic receptor, muscarinic 3 (M3)

Target Class
GPCR
Family
Acetylcholine
Official Symbol
CHRM3
Species
Human
Accession Number
AF498917
Alias Names
EGBRS; HM3; acetylcholine receptor, muscarinic 3; cholinergic receptor, muscarinic 3; m3 muscarinic receptor; muscarinic acetylcholine receptor M3
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Acetylcholine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin U2OS Human 93-0860C3
Internalization U2OS Human 93-0775C3
Assay Readout Background Species Assay Kit
Internalization U2OS Human 93-0775E3CP5S
Internalization U2OS Human 93-0775E3CP5M
Internalization U2OS Human 93-0775E3CP5L
β-Arrestin U2OS Human 93-0860E3CP0S
β-Arrestin U2OS Human 93-0860E3CP0M
β-Arrestin U2OS Human 93-0860E3CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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