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Cholinergic receptor, muscarinic 1 (M1)

Target Class
GPCR
Family
Acetylcholine
Official Symbol
CHRM1
Species
Human
Accession Number
AF498915
Alias Names
HM1; M1; M1R; acetylcholine receptor, muscarinic 1; cholinergic receptor, muscarinic 1; muscarinic acetylcholine receptor M1
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Acetylcholine
?

DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin U2OS Human 93-0859C3
Internalization U2OS Human 93-0655C3
Assay Readout Background Species Assay Kit
β-Arrestin U2OS Human 93-0859E3CP0S
β-Arrestin U2OS Human 93-0859E3CP0M
β-Arrestin U2OS Human 93-0859E3CP0L
Internalization U2OS Human 93-0655E3CP5S
Internalization U2OS Human 93-0655E3CP5M
Internalization U2OS Human 93-0655E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
        Available  
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