Chemokine (C-C motif) receptor-like 2 (CCRL2)
- Target Class
- GPCR
- Family
- Chemokine
- Official Symbol
- CCRL2
- Species
- Human
- Accession Number
- NM_003965
- Alias Names
- C-C chemokine receptor-like 2; CKRX; CRAM; CRAM-A; CRAM-B; HCR; chemokine (C-C motif) receptor-like 2; chemokine receptor CCR11; chemokine receptor X; putative MCP-1 chemokine receptor
- Background
This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Chemokine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0333C2A |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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