Chemokine (C-C motif) receptor 7 (CCR7)

Target Class
GPCR
Family
Chemokine
Official Symbol
CCR7
Species
Human
Accession Number
AY587876
Alias Names
BLR2; C-C CKR-7; C-C chemokine receptor type 7; CC chemokine receptor 7; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced G-protein coupled receptor; Epstein-Barr virus induced gene 1; MIP-3 beta receptor; chemokine (C-C motif) receptor 7; chemokine (C-C) receptor 7; epstein-Barr virus-induced G-protein coupled receptor 1; lymphocyte-specific G protein-coupled peptide receptor
Background
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Chemokine
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin HEK 293 Human 93-0195C1
β-Arrestin CHO-K1 Human 93-0195C2
Internalization U2OS Human 93-0740C3
cAMP CHO-K1 Human 95-0070C2
Chem-1 Human HTS012C
Assay Readout Background Species Assay Kit
cAMP CHO-K1 Human 95-0070E2CP2M
cAMP CHO-K1 Human 95-0070E2CP2L
β-Arrestin HEK 293 Human 93-0195E1CP0M
β-Arrestin HEK 293 Human 93-0195E1CP0L
β-Arrestin CHO-K1 Human 93-0195E2CP0M
β-Arrestin CHO-K1 Human 93-0195E2CP0L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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