Vasopressin receptor 1B (V1B)
- Target Class
- GPCR
- Family
- Vasopressin and Oxytocin
- Official Symbol
- AVPR1B
- Species
- Human
- Accession Number
- NM_000707.3
- Alias Names
- AVPR V1b; AVPR V3; AVPR3; V1bR; antidiuretic hormone receptor 1B; arginine vasopressin receptor 1B; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; vasopressin V1b receptor; vasopressin V3 receptor
- Background
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
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Solution Portfolio
Related Family Members:
Vasopressin and Oxytocin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family
| Assay Readout |
Background |
Species |
Cell Line |
| β-Arrestin |
CHO-K1 |
Human |
93-0486C2 |
| Internalization |
U2OS |
Human |
93-0722C3 |
| KINOMEscan |
TKscan |
BROMOscan |
NHRscan |
GPCRscan |
PATHscan |
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Available |
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