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Vasopressin receptor 1B (V1B)

Target Class
GPCR
Family
Vasopressin and Oxytocin
Official Symbol
AVPR1B
Species
Human
Accession Number
NM_000707.3
Alias Names
AVPR V1b; AVPR V3; AVPR3; V1bR; antidiuretic hormone receptor 1B; arginine vasopressin receptor 1B; arginine vasopressin receptor 3; pituitary vasopressin receptor 3; vasopressin V1b receptor; vasopressin V3 receptor
Background
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Family Members:

Vasopressin and Oxytocin
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Readout Background Species Cell Line
β-Arrestin CHO-K1 Human 93-0486C2
Internalization U2OS Human 93-0722C3
Assay Readout Background Species Assay Kit
β-Arrestin CHO-K1 Human 93-0486E2CP0S
β-Arrestin CHO-K1 Human 93-0486E2CP0M
β-Arrestin CHO-K1 Human 93-0486E2CP0L
Internalization U2OS Human 93-0722E3CP5S
Internalization U2OS Human 93-0722E3CP5M
Internalization U2OS Human 93-0722E3CP5L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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