Ion channels continue to be an important therapeutic target for a range of indications including arrhythmia, hypertension, local anesthesia, pain, stroke, epilepsy, depression, bipolar disorder, cystic fibrosis, cardiac arrhythmias, COPD, autoimmune disorders, and diabetes. Ion channels are not only significant drug targets, but they are also critical for evaluating drug safety.
Over 60 targets, from voltage-gated channels to slow and fast ligand-gated channels
Pharmacologically and functionally validated using our in-house discovery and safety service panels
Biophysical and pharmacological properties characterized using conventional and automated patch clamp platforms by experienced electrophysiologists
Proprietary cell line vector technologies for optimum stability, expression, and uniform current