| Biological Information | |
|---|---|
| Background Information: | Pyruvate dehydrogenase kinase isoenzyme 4 (PDHK4) is a member of the PDK/BCKDK protein kinase family. PDHK4 plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. PDHK4 is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. [provided by RefSeq, Mar 2010] |
| Target Class: | Kinase |
| Accession Number: | NM_002612.2 |
| Target Name: | PDHK4 |
| Target Aliases: | PDK4, Pyruvate Dehydrogenase Kinase 4, Pyruvate Dehydrogenase Kinase, Isozyme 4 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
PDHK4, active
10 µg of active PDHK4. N-terminal GST-tagged, recombinant, human PDHK4 full length.
Datasheets
15-024x Datasheet
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