The PathHunter® Epoetin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses erythropoietin or Epoetin Alfa-induced dimerization of EPOR receptors. This product uses EFC technology. The included cells overexpress EPOR target protein fused to PK alongside EPOR target protein fused to EA. Upon ligand-induced dimerization of EPOR, detectable EFC signal is produced. This assay has been optimized and qualified with Aranesp® (not supplied in the bioassay kit). Aranesp® is a registered trademark of Amgen Inc. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates.
Prolactin Receptor Family
EPO-R, Erythropoietin receptor
Potency; Commercial Release & Stability
Store in vapor phase of liquid nitrogen.
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Aranesp® is a registered trademark of Amgen Inc.
PathHunter® Epoetin Alfa Bioassay Kit
The PathHunter® Epoetin Alfa Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses erythropoietin or Darbepoetin Alfa-induced dimerization of EPOR receptors.
View bioassay qualification data.