| Biological Information | |
|---|---|
| Background Information: | CSF1R (colony stimulating factor I receptor), formerly known as FMS (McDonough feline sarcoma viral oncogene), is a receptor tyrosine kinase for CSF-1 and expressed primarily in monocytes, macrophages, and human tumor tissue. CSF-1 binding to FMS induces dimerization of the tyrosine kinase domain of the receptor, and stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series.
GenBank U63963 |
| Target Class: | Kinase |
| Accession Number: | NM_005211.2 |
| Target Name: | Fms |
| Target Aliases: | CSF1R, FIM2, CSF-1-R, C-FMS, CSFR, c-fms, CD115, FMS |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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Fms, active
N-terminal 6His-tagged recombinant, human Fms amino acids 538-end.
Datasheets
14-551x Datasheet
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