| Biological Information | |
|---|---|
| Background Information: | Aurora C Protein is a member of the Aurora subfamily of serine/threonine protein kinases. It is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
GenBank AB017332.1 / GenBank NM_020238.2 |
| Target Class: | Kinase |
| Accession Number: | NP_001015878 |
| Target Name: | Aurora C |
| Target Aliases: | AIK32 3, ARK-3, STK13, ARK3, AurC |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Aurora C, active
N-terminal 6His-tagged recombinant, human Aurora C amino acids 35-end and N-terminal GST-tagged recombinant, human INCENP amino acids 821-end.
Datasheets
14-911x Datasheet
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