Biological Information

Background Information:

Aurora C Protein is a member of the Aurora subfamily of serine/threonine protein kinases. It is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.  GenBank AB017332.1 / GenBank NM_020238.2

Target Class:

Kinase

Family:

Other Protein Kinase

Sub Family:

Protein Ser/Thr

Protein Name:

Aurora-C

Protein Aliases:

Aurora 3|Aurora/IPL1-related kinase 3|ARK-3|Aurora-related kinase 3|Aurora/IPL1/Eg2 protein 2|Serine/threonine-protein kinase 13|Serine/threonine-protein kinase aurora-C

Accession Number:

NP_001015878

UniProt Number:

Q9UQB9

Gene Name:

AURKC

Gene ID:

6795

Gene Aliases:

AurC|ARK3

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

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Assay Information

Assay Type:

Enzymatic