Biological Information
Background Information:
TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus. GenBank NM_003328
Target Class:
Kinase
Family:
TK
Sub Family:
Protein Tyrosine
Protein Name:
TXK
Protein Aliases:
Protein-tyrosine kinase 4|Resting lymphocyte kinase
Accession Number:
NM_003328
UniProt Number:
P42681
Gene Name:
TXK
Gene ID:
7294
Gene Aliases:
TKL|PSCTK5|BTKL|RLK
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
Enzymatic
Clinical Relevance
Therapeutic Area:
Inflammation/Allergy