Biological Information

Background Information:

TxK (TxK Tyrosine Kinase) is a ,on-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. It predicted to enable non-membrane spanning protein tyrosine kinase activity. TXK is also involved in positive regulation of interferon-gamma-mediated signaling pathway, positive regulation of macromolecule metabolic process, and protein autophosphorylation. TXK is located in cytoplasm and nucleus. GenBank NM_003328

Target Class:

Kinase

Family:

TK

Sub Family:

Protein Tyrosine

Protein Name:

TXK

Protein Aliases:

Protein-tyrosine kinase 4|Resting lymphocyte kinase

Accession Number:

NM_003328

UniProt Number:

P42681

Gene Name:

TXK

Gene ID:

7294

Gene Aliases:

TKL|PSCTK5|BTKL|RLK

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy