Biological Information

Background Information:

N-terminal 6His-tagged, recombinant, human TAF1L, amino acids 1428-end. TAF1L may act as a functional substitute for TAF1/TAFII250 during male meiosis, when sex chromosomes are transcriptionally silenced. The kinase has been implicated in oral squamous cell carcinoma and other cancers, suggesting a potential role in tumorigenesis.

Target Class:

Kinase

Family:

TAF1

Sub Family:

Serine/threonine kinase

Protein Name:

TAF1L

Protein Aliases:

TAF(II)210

Accession Number:

NM_153809.1

UniProt Number:

Q8IZX4

Gene Name:

TAF1L

Gene ID:

138474

Gene Aliases:

TAF2A2; TAF(II)210

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

1 year at -70°C

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Enzymatic

Assay Measures:

Radiometric, ADP Accumulation

Bioassay Data

Trademark Statement:

For Research Use Only

Clinical Relevance

Therapeutic Area:

Oncology