Biological Information
Background Information:
NEK (NIMA-Related Kinase) Ser/Thr kinase family includes at least 11 members and is involved in regulation of mitosis. Overexpression of active NEK2 (NLK1) induces a striking splitting of centrosomes, whereas prolonged expression of either active or inactive NEK2 leads to dispersal of centrosomal material and loss of a focused microtubule-nucleating activity. GenBank NM_002497
Target Class:
Kinase
Family:
Other Protein Kinase
Sub Family:
Protein Ser/Thr
Protein Name:
NEK2
Protein Aliases:
HsPK 21|protein phosphatase 1, regulatory subunit 111
Accession Number:
NM_002497.2
UniProt Number:
P51955
Gene Name:
NEK2
Gene ID:
4751
Gene Aliases:
NLK1|NEK2A|RP67|PPP1R111
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
1 year at -70°C
Usage disclaimer:
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Assay Information
Assay Type:
Enzymatic
Bioassay Data
Trademark Statement:
For Research Use Only
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology