Biological Information

Background Information:

Serine/threonine-protein kinase 3 STK3 (Mammalian STE20-like kinase 2, MST2, Serine/threonine-protein kinase Krs-1, ST2) has been shown to be activated in cellular apoptosis induced by a variety of stimuli. In most cases, MST2 activation during apoptosis has been reported to accompany caspase-3 cleavage of the enzyme. A few studies have also implicated protein phosphorylation reactions in MST2 regulation. GenBank U60206

Target Class:

Kinase

Family:

STE

Sub Family:

Protein Ser/Thr

Protein Name:

MST2

Accession Number:

NM_006281.2

UniProt Number:

Q13188

Gene Name:

STK3

Gene ID:

6788

Gene Aliases:

MST2|KRS1

Target Species:

Human

Usage

Product Type:

Enzymes

Application:

Drug Discovery & Development

Storage Conditions:

6 months at -70°C

Usage disclaimer:

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Assay Information

Assay Type:

Enzymatic

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology