DAPK1, active

Background Information:

Death-associated protein kinase 1 (DAPK1) is a calcium/calmodulin-dependent kinase that phosphorylates serine/threonine residues on proteins. DAPK1 modulates cell death induced by IFN-γ, TNF-α, Fas, and detachment from the extracellular matrix. DAPK1 has been also implicated in TGF-β-induced apoptosis in several cultured cell lines in which Smad proteins mediate transcriptional activation of DAPK1. GenBank NM_004938

Target Class:

Kinase

Family:

CAMK

Sub Family:

Protein Ser/Thr

Protein Name:

DAPK1

Accession Number:

NM_004938.2

UniProt Number:

P53355

Gene Name:

DAPK1

Gene ID:

1612

Gene Aliases:

DAPK

Target Species:

Human