Biological Information

Background Information:

The ChemiSCREEN™ CXCR1 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR1 surface expression. ChemiSCREEN™ membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression.

Target Class:

GPCR

Family:

Chemokine

Sub Family:

Class A

Protein Name:

CXCR1 (IL-8RA)

Protein Aliases:

CXCR-1|CDw128a|High affinity interleukin-8 receptor A|IL-8R A|IL-8 receptor type 1|CD antigen CD181

Accession Number:

M68932

UniProt Number:

P25024

Gene Name:

CXCR1

Gene ID:

3577

Gene Aliases:

CKR-1|CDw128a|CD181

Target Species:

Human

Cell Background:

Chem-1

Usage

Product Type:

Membrane Preparations

Application:

Drug Discovery & Development

Storage Conditions:

Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles.

Usage disclaimer:

These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.

Assay Information

Assay Type:

Cell Based

Assay Measures:

Binding

Detection Method:

Fluorescence, Radioactivity

Additional Information

Brand:

ChemiSCREEN™