Plk1, active

N-terminal 6His-tagged recombinant, human Plk1.

Catalog #: 14-777

$399.00$2,989.00


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Biological Information
Background Information:
Polo-like kinases (PLKs) are a family of serine/threonine kinases related to the polo gene product of Drosophila melanogaster, originally identified from a mitotic mutant that displayed abnormal spindle poles. PLKs play essential roles in several stages of mitosis and cytokinesis with a dynamic pattern of localization to centrosomes, kinetochores and central spindle structures during the cell cycle. PLK1 has been shown to be overexpressed in many human tumors, such as non-small cell lung cancer, squamous cell carcinomas of the head and neck, melanomas, oropharyngeal carcinomas, and ovarian and endometrial carcinomas. GenBank NM_005030
Target Class:
Kinase
Accession Number:
NM_005030
Target Name:
Plk1
Target Aliases:
PLK, PLK1, STPK13
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-777x Datasheet

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