EphA3, active

N-terminal 6His-tagged recombinant, human EphA3 amino acids 578-end.

Catalog #: 14-644

$399.00$2,989.00


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Biological Information
Background Information:
Eph family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Recruitment of CrkII and activation of Rho Signaling are responsible for EphA3-mediated cell rounding, blebbing and de-adhesion. This response is activated by ephrin-A5-mediated receptor clustering and EphA3 tyrosine kinase activity. GenBank NM_005233
Target Class:
Kinase
Family:
Receptor Typosine Kinase (RTK): Growth Factor Receptor
Accession Number:
NM_005233.3; NM_182644.1
Target Name:
EphA3
Target Aliases:
EPHA3, HEK4, ETK1, HEK, TYRO4, ETK, EphA3
Target Species:
Human
Usage
Product Type:
Enzymes
Application:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
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Datasheets

14-644x Datasheet

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