Biological Information | |
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Background Information: | BMX (also called ETK, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase) is one of the non-receptor tyrosine kinases, located intracellularly. It is a Src homolog and contains an SH3 and SH2 domain upstream from the tyrosine kinase domain. Unlike other members of the BTK family kinases, which are mostly hemopoietic cell-specific, BMX is preferentially expressed in epithelial and endothelial cells of large arteries. Inhibitors of BMX may be useful in the treatment of atherosclerosis and cancer.
GenBank NM_001721 |
Target Class: | Kinase |
Accession Number: | NM_001721.4; NM_203281.1 |
Target Name: | Bmx |
Target Aliases: | BMX, PSCTK2, PSCTK3, NTK38, ETK |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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