Biological Information | |
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Background Information: | AMPK (α1, β1, γ1) protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
GenBank AF100763 / GenBank NM_006253 / GenBank NM_002733 |
Target Class: | Kinase |
Accession Number: | AF100763; NM_006253; NM_002733 |
Target Name: | AMPK (α1, β1, γ1) |
Target Aliases: | PRKAB1, PRKAG1, PRKAA1 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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AMPK (alpha1, beta1, gamma1), active
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