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Trademarks referenced herein are either registered trademarks of or trademarks of Eurofins DiscoverX as used in US and/or in other countries. Any rights not expressly granted herein are reserved.

Eurofins DiscoverX^®	BioMAP^®	Bioseek	BROMOscan^®	SAFETYscan^®	GPCRscan
HitHunter^®	KdELECT^®	KILR^®	KINOMEscan^®	LeadHunter^®	PathHunter^®
ProLabel^®	scanEDGE^®	scanELECT^®	scanMAX^®	scanMODE	Diversity PLUS^®
PrecisION^™	TREEspot^®	AssayComplete^™	cAMP Hunter^™	ProLink^™	eXpress^™
InCELL Hunter^™	InCELL Pulse^™	ChemiSCREEN^™	SPRINTer^™

Technology	Patent No.^*	Products are subject to label license **
PathHunter^® Activated GPCR internalization Assay	6,342,345 7,223,537 8,101,373 8,211,655	YES
PathHunter^® Total GPCR internalization Assay	6,342,345 7,223,537 8,426,138	YES
Protein Translocation Assay PathHunter^® RTK Assay Internalization Platform	6,342,345 7,223,537 8,101,373 8,586,294 8,679,832	YES
PathHunter^® NHR Protein Translocation Assay platform	8,865,421	YES
PathHunter^® Pharmacochaperone Trafficking Assay	6,342,345 7,223,537 8,569,057 9,388,449	YES
Protein: Protein Interaction Assay Platform PathHunter^® Dimerization Assay PathHunter^® β-arrestin GPCR Assay	6,342,345 7,223,537 8,101,373 8,541,175 8,679,832	YES
InCell Hunter^™ Target Engagement Cell Based Assay	8,945,853	YES
RTK and Non-Receptor CTK Assay	6,342,345 7,223,537 8,101,373 8,067,155	YES
Protein Degradation Assay-Pathway Studies	7,479,377	YES
Calcium No Wash Plus Assay		YES
ADP accumulation Assay	7,410,755	NO
Kinomescan^® Technology	9,110,054 7,897,381 7,833,741 7,112,435 10,324,092	NO
Biomap^® Technology	6,656,695 6,593,511 7,266,458 7,912,651 8,019,551 8,718,945 8,697,387 8,467,970 9,734,282 10,018,621 10,245,255 B2	NO
PathHunter^® β-Arrestin2 Retroparticles		YES
KILR™ Cytotoxicity Kit		YES
ProLink™ 1 Vector	8,679,832	YES
ProLink™ 2 Vector	8,101,373	YES

Products/Services utilizing HEK 293 cells - This is sold under a license from AdVec Inc.

* In addition to the US patent no. as listed above, the product/technology might also be covered by issued foreign patents and/or pending patent application.

** See Limited Use Label License for the use of Virus Based Product (AGREEMENT 1); Vectors (AGREEMENT-1); Kits (AGREEMENT-1); Parental Cell Lines (AGREEMENT-1); Bioassay Kits AGREEMENT-3); Target Specific Cell Line (AGREEMENT-2); Cell Pools (AGREEMENT-2); Calcium No Wash Plus Product (AGREEMENT-4)

AGREEMENT-1AGREEMENT-2 AGREEMENT-3AGREEMENT-4

LIMITED USE LABEL LICENSE AGREEMENT-1

(Parental Cell Lines, Virus Based Products, Vectors and Kits, wherein each product is either sold individually or as a combination product referred to herein as a “Product”)

This product is for in vitro use only and in no event can this Product be used in whole animals. The right to use or practice the inventions in the foregoing patents (including method of use claims) by using or propagating this Product is granted solely in connection with the use of appropriate Detection Reagents (protected under trade secret) purchased from DiscoverX Corporation or its authorized distributors.

The Product and associated components (collectively referred to as “Materials”) as purchased from DiscoverX are expressly restricted in their use. By purchasing and using the Materials, the purchaser agrees to comply with the following terms and conditions of this label license agreement and recognizes and agrees to such restrictions:

1) The Product is transferable within different sites of purchaser only but is not transferable to any third parties or Contract Research Organization (CRO) without explicit written permission from DiscoverX. Transfer to a third party site for any use will be permitted only upon written request by purchaser followed by subsequent written approval by DiscoverX.

2) The Detection Reagents contain or are based upon the proprietary and valuable know-how developed by DiscoverX, and the Detection Reagents have been optimized by DiscoverX to function more effectively with the Product. Purchaser will not analyze or reverse engineer the Materials nor have them analyzed on purchaser’s behalf.

3) In using the Product, purchaser will use Detection Reagents supplied by DiscoverX or an authorized DiscoverX distributor for the Materials.

4) The purchaser cannot sell or otherwise transfer the Product or associated components to a third party or use for commercial purposes. Commercial purposes means any activity by a party for consideration and may include, but is not limited to (1) use of the Product or associated components to provide a service, information or data to a third party and/or (2) resale of the Product or associated components, whether or not such Product or its components are resold for use in research.

If the purchaser is not willing to accept the limitations of this label license agreement and/or has any further questions regarding the rights conferred with purchase of the Product or Material, please contact:

DiscoverX Corporation
Attn: Licensing Department
42501 Albrae Street, Suit 100
Fremont, CA 94538
tel | 510.771.3527
Agreements@discoverx.com

LIMITED USE LABEL LICENSE AGREEMENT-2

PathHunter®, KILR®, InCELL Hunter™ and InCELL Pulse™

(Target Specific Cell Lines and Cell Pools wherein each Product is either sold individually or as a combination product referred to herein as a “Product”)

This product is for in vitro use only and in no event can this Product be used in whole animals. This Product and its use is currently subject of pending U.S. and/or foreign patent applications. The right to use or practice the inventions by using or propagating this Product is granted solely in connection with the use of appropriate Detection Reagents (protected under trade secret) purchased from Eurofins DiscoverX Corporation or its authorized distributor ('DiscoverX').

By purchasing and using the Product, the purchaser agrees to comply with the following terms and conditions of this label license and recognizes and agrees to such restrictions:

1)   The Product is transferable within different sites of purchaser only but is not transferable to any third parties or Contract Research Organization (CRO) without explicit written permission from DiscoverX. Transfer to a third party site for any use will be permitted only upon written request by purchaser followed by subsequent written approval by DiscoverX.

2)   The Detection Reagents contain or are based upon the proprietary and valuable know-how developed by DiscoverX, and the Detection Reagents have been optimized by DiscoverX to function more effectively with the Product. Purchaser will not analyze or reverse engineer the Product and/or Detection Reagents nor have them analyzed on purchaser’s behalf.

3)   In using the Product, purchaser will use Detection Reagents supplied by DiscoverX or an authorized DiscoverX distributor for the Product.

cAMP Hunter™, ChemiSCREEN™, ChemiBRITE™, and PrecisION®

(Cell Lines referred to herein as the “Product”)

The Product as purchased by the purchaser (the “Purchaser”) from Eurofins Discovery (the “Eurofins”) are expressly restricted in their use. By purchasing and using the Product, the Purchaser agrees to comply with the following terms and conditions of this license agreement (this “Agreement”).

1) By purchasing the Product, Eurofins hereby grants to the Purchaser, a royalty-free and non-exclusive license to use the Product for Research Purposes only, whether the Purchaser is an academic user or a for-profit entity. “Research Purposes” shall mean any biological research and development application or use, including without limitation, development, demonstrations, or validation of biological assays, life sciences and/or pharmaceutical research.

2) Purchaser agrees that the Product will be used by the Purchaser only and will not be transferred to any third party sites or a Contract Research Organization (CRO) without explicit written permission from Eurofins.

3) The Purchaser shall not analyze or reverse engineer the Product nor have them analyzed on Purchaser’s behalf.

4) The Purchaser cannot sell or otherwise transfer the Product to a third party or a CRO or use for Commercial Purposes. “Commercial Purposes” means any activity by Purchaser that may include, but is not limited to (a) operating a service business that uses the Product to develop information or data which is resold for research and development applications; (b) use of the Product in manufacturing; (c) use of the Product for therapeutic, diagnostic, or prophylactic purposes; or (d) resale of the Product, whether or not such Product are resold for use in research.

If the Purchaser is not willing to accept the limitations of this Agreement and/or has any further questions regarding the rights conferred with purchase of the Product, please contact:

Attn: Contracts Department Email: contractservicesEPDS@eurofins.com

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