Webinars & Online Seminars

An online learning resource

DiscoverX offers a number of upcoming and previously recorded webinars, recorded online meetings and presentations with our scientists that cover a variety of relevant topics, tools and data analysis techniques.

 
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Webinar: Protein Degradation (PROTACs...
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Event Date ▼ Event Name PDF Link Webinar Link
October 9, 2019 Webinar: Establishing Qualified Bioassays for Checkpoint Receptors to Implement in QC Lot Release: Case Studies on PD-1 and SIRPα - 60 min.
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May 9, 2018 Webinar: Accelerate Biologics and Biosimilars Development: Case Studies Implementing Robust and Simple Potency Bioassays - 60 min.
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December 6, 2017 Webinar: Application of β-Arrestin Assays to the Orphan GPCR World - 30 min.
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November 29, 2017 Webinar: Implementing ADCC assays in QC: When donor variability isn’t an option - 55 min.
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November 1, 2017 Webinar: How to Accelerate Your Biotherapeutic Development with Cell-Based Assay Services - 40 min.

What will be covered?

  • How PathHunter services save development time compared to in-house assays
  • Screening and profiling biologics with highly specific and sensitive assays that produce robust and reproducible results
  • Example data from marketed drugs, like Pembrolizumab and Nivolumab, using these cell-based assays
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September 20, 2017 Webinar: Create Your Own Cell-Based Assays to Study Receptor Tyrosine Kinase Function - 30 min.

What will be covered?

  • RTK biology and drug discovery importance
  • Tools needed to create your own RTK cell lines and assays
  • Experimental design and workflows
  • Applications of RTK and related cell-based assays
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June 28, 2017 BIOtech Japan 2017
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June 27, 2017 Webinar: Driving Robust ADCC and T Cell Redirection with KILR® CD16 Effector Cells - 55 min.

What will be covered?

  • Eliminating donor variability in cytotoxicity assays with single donor-derived primary human KILR CD16 Effector Cells
  • Better analysis of antibody’s cytotoxicity profile with better Hill Slopes and higher S:B compared to PBMCs
  • Faster assessment of redirected T cell-mediated cytotoxicity with rapid killing kinetics of the CD16 Effector cells
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June 27, 2017 Drug Repositioning, Repurposing and Rescue Conference 2017
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May 18, 2017 Create Your Own Cellular Target Engagement Assay - 30 min.

What will be covered?

  • Overview of compound-target engagement
  • Tools and workflow to create your own cell-based target engagement assay
  • Applications of InCELL Pulse assays
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May 1, 2017 PEGS Summit 2017
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April 19, 2017 Webinar: Combining Target-Based and Phenotypic Discovery Assays for Drug Repurposing - 40 min.

What will be covered?

  • Using phenotypic profiling to characterize clinically successful drugs for a given indication
  • Combining target-based and phenotypic data to prioritize drugs for repurposing
  • Understanding how multi-targeted kinases can be pivoted towards new indications
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April 5, 2017 Webinar: From Chemistry to Clinic: Discovery of Biased Apelin Receptor Agonists and Action in the Cardiovascular System - 55 min.

What will be covered?

  • Role of GPCRs in human cardiovascular system
  • Strategies for exploiting orphan GPCRs recently paired with endogenous ligands illustrated by Apelin and Elabela/Toddler
  • Identifying biased agonists using pharmacologically-relevant functional cell based assays
  • Validating assays and minimizing inter-assay variation
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March 29, 2017 Webinar: Creating Cellular Target Engagement Assays for Diverse Kinases Using InCELL Pulse™ - 30 min.

What will be covered?

  • Overview of compound-target engagement and InCELL Pulse platform
  • Kinase drug discovery importance
  • Tools and workflow needed to create your own target engagement assay
  • Validation data showing several examples of diverse kinases
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March 14, 2017 Immune Checkpoint Inhibitors 2017
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March 10, 2017 免疫チェックポイント阻害剤の評価に適切なセルベースアッセイ系のご紹介 - 60 min.

What will be covered?

  • 抗腫瘍免疫応答が増強に活用される免疫チェックポイント阻害剤の評価系
  • PD-1, PD-L1, PD-L2, TWEAK, CD40, OX40, VISTA などの実施例
  • 放射性同位体を使用しないADCC(抗体依存性細胞傷害)の評価系
  •  
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March 9, 2017 Webinar: Mu Opioid Receptor Splicing and Signaling: Another Dimension of GPCR Function - 55 min.

What will be covered?

  • Overview of the mu opioid receptor signaling
  • GPCR splicing, using OPRM1 as an example
  • Region and cell specific splicing
  • Functional consequences of 5’ splicing
  • Functional consequences of 3’ splicing
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March 8, 2017 US Bioassay Conference (BEBPA) 2017
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November 30, 2016 Webinar: Create Your Own InCELL Pulse™ Cellular Compound-Target Engagement Assay - 60 min.

What will be covered?

  • Overview of compound-target engagement
  • Tools needed to create your own target engagement assay
  • Experimental design and workflow
  • Applications of InCELL Pulse assays
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November 9, 2016 Webinar: Duplexed Screening of GPCRs to Measure Calcium and β-Arrestin - 60 min.

What will be covered?

  • Screening approaches for GPCR drug discovery
  • Creating a duplexed assay to monitor calcium and β-arrestin in a single well
  • Determine potential bias for various drugs and define potency ranking
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October 26, 2016 Webinar: Target to Phenotype: Tools to Accelerate Your Immuno-Oncology Drug Pipeline - 60 min.

What will be covered?

  • Challenges in immuno-oncology drug development
  • Tools to expedite and simplify any immuno-oncology drug development pipeline
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September 30, 2016 Webinar: Immuno-Oncology Drug Development: Profiling Immunomodulatory Biologics and Compounds in Human Primary Cell-Based Oncology Models - 60 min.

What will be covered?

  • Overview of the BioMAP® immuno-oncology/oncology systems
  • Information BioMAP iOnc studies provide
  • Host stromal/vascular - tumor microenvironment biology
  • Case studies of profiling Ab therapies (anti-PD-1, anti-CTLA-4, etc.) and preclinical compounds
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August 10, 2016 Webinar: New Tricks for Old Drugs: An Unbiased Phenotypic Approach to Drug Repurposing - 40 min.

What will be covered?

  • Overview of the BioMAP Diversity PLUS phenotypic screening platform's modeling of broad human tissue and disease biology
  • Details of how Diversity PLUS profiling guides new indications for marketed drugs and pre-clinical candidates
  • Examples highlighting how this technology is used to support repositioning of approved drugs for alternate indications
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May 25, 2016 Webinar: A Phenotypic Platform for Characterization of Drug Safety Mechanisms in Human Primary Cell Disease Models - 40 min.

What will be covered?

  • How to maximize knowledge of your compounds using the BioMAP® Diversity PLUS™ panel of human primary cells systems
  • How to understand mechanism classification analysis and toxicity signatures
  • A case study on discovery of a mechanism-based novel signature for skin irritation
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May 19, 2016 Webinar: Ready-to-use Potency Assays for Anti-VEGF Drugs Like Bevacizumab, Ranibizumab & Aflibercept - 60 min.

What will be covered?

  • Creation of cell-based bioassays for potency and stability testing
  • Application, development and validation of assays with drug molecule
  • Case studies on Avastin (bevacizumab), Eylea (aflibercept) and Lucentis (ranibizumab)
  • Qualified assays for > 30 biosimilars
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November 10, 2013 2013 AAPS Annual Meeting and Exposition
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October 28, 2013 FAST 2013: Functional Analysis & Screening Technologies
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October 17, 2013 14th Annual G Protein-Coupled Receptor (GPCR) Retreat
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September 24, 2013 11th Annual Discovery on Target
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July 23, 2013 EpiCongress
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July 8, 2013 8th Protein Kinases in Drug Discovery
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June 17, 2013 Next-Gen Kinase Inhibitors
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June 5, 2013 World Pharma Congress
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May 7, 2013 Merck Technology Symposium
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April 30, 2013 CHI - PEG Summit
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April 25, 2013 ASPET - 4th GPCR Colloquium
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April 16, 2013 CHI - Drug Discovery Chemistry
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April 6, 2013 American Association for Cancer Research
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March 20, 2013 Epigenetic Marks and Cancer Drugs
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March 20, 2013 GTC: 2nd Inflammatory and Immunological BioMarkers Meeting
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March 19, 2013 ELRIG - Research & Innovation
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March 14, 2013 SGC
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March 11, 2013 Society of Toxicology
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March 7, 2013 The 1st International Congress on Controversies in Personalized Oncology
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February 25, 2013 3rd Ubiquitin Research and Drug Discovery
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January 14, 2013 2013 SLAS Conference & Exhibition
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January 13, 2013 SLAS Satellite Symposium at the Sanford-Burnham Medical Research Institute in Lake Nona
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October 17, 2012 GPCR Retreat
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October 13, 2012 Society for Neuroscience (SfN)
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October 4, 2012 DiscoveRx Technology Symposium
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October 1, 2012 CHI-DOT 2012
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September 25, 2012 MipTec 2012 - DiscoveRx Technology Symposium
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September 24, 2012 MipTec 2012
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September 20, 2012 Eurpoean DiscoveRx Technology Symposium - Cambridge
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September 18, 2012 European DiscoveRx Technology Symposium - Born
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September 12, 2012 DiscoveRx Technology Symposium - San Diego
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June 19, 2012 SLAS Asia 2012
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June 4, 2012 CHI - Next Gen Kinase Inhibitors
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May 30, 2012 7th Protein Kinases In Drug Discovery
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May 8, 2012 16th Annual Merck Technology Symposium Exhibitor Site
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April 30, 2012 Eighth Annual PEGS
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Society for Laboratory Automation & Screening 2017
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IMMUNOLOGY 2017
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CASSS Bioassays 2017
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