HTS Rapid Generation of Highly Potent and Selective Kinase HIT Compounds

HTS Rapid Generation of Highly Potent and Selective Kinase HIT Compounds
Version:
21284

File Name/Number:
HTS SLAS

Year:
2022

 

A Case Study on the Design of an Efficient HTS Cascade Focused on the PIM3 Kinase.

 

Kinases are highly druggable targets, often playing a pivotal role within pathways involved in disease physio-pathology and therefore of interest across a wide range of therapeutic indications, in particular oncology.