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Kinase Targets by Technology

AAK1 ABL1 ABL1(E255K)-phosphorylated ABL1(F317I)-nonphosphorylated ABL1(F317I)-phosphorylated
ABL1(F317L)-nonphosphorylated ABL1(F317L)-phosphorylated ABL1(H396P)-nonphosphorylated ABL1(H396P)-phosphorylated ABL1(M351T)-phosphorylated
ABL1(Q252H)-nonphosphorylated ABL1(Q252H)-phosphorylated ABL1(T315I)-nonphosphorylated ABL1(T315I)-phosphorylated ABL1(Y253F)-phosphorylated
ABL1-nonphosphorylated ABL1-phosphorylated ABL2 ACVR1 ACVR1B
ACVR1B/BMPR2 ACVR1C/ACVR2 ACVR1C/ACVR2B ACVR2/ACVR1 ACVR2A
ACVR2B ACVRL1 ACVRL1/ACVR2 ACVRL1/ACVR2B ACVRL1/BMPR2
ADCK3 ADCK4 AKT1 AKT2 AKT3
ALK ALK(1151Tins) ALK(C1156Y) ALK(F1174L) ALK(L1196M)
AMPK-alpha1 AMPK-alpha2 ANKK1 ARK5 ASK1
ASK2 AURKA AURKB AURKC AXL
BIKE BLK BMPR1A BMPR1A/ACVR2 BMPR1A/ACVR2B
BMPR1A/BMPR2 BMPR1B BMPR1B/ACVR2 BMPR1B/ACVR2B BMPR1B/BMPR2
BMPR2 BMX BRAF BRAF(V600E) BRK
BRSK1 BRSK2 BTK BUB1 CAMK1
CAMK1B CAMK1D CAMK1G CAMK2A CAMK2B
CAMK2D CAMK2G CAMK4 CAMKK1 CAMKK2
CASK CDC2L1 CDC2L2 CDC2L5 CDK1
CDK10 CDK11 CDK12 CDK2 CDK20
CDK3 CDK4 CDK4-cyclinD1 CDK4-cyclinD1(F93L) CDK4-cyclinD3
CDK5 CDK6 CDK7 CDK8 CDK9
CDKL1 CDKL2 CDKL3 CDKL5 CHEK1
CHEK2 cINSRa cINSRb CIT c-KIT
CLK1 CLK2 CLK3 CLK4 c-MET/c-MET
c-Ret-GFRα1 c-Ret-GFRα2 CSF1R CSF1R/CSF1R CSF1R-autoinhibited
CSF3R-JAK1 CSK CSNK1A1 CSNK1A1L CSNK1D
CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CSNK2A1
CSNK2A2 CTK DAPK1 DAPK2 DAPK3
DCAMKL1 DCAMKL2 DCAMKL3 DDR1 DDR2(T654M)
DLK DMPK DMPK2 DRAK1 DRAK2
DYRK1A DYRK1B DYRK2 EGFR EGFR(E746-A750del)
EGFR(G719C) EGFR(G719S) EGFR(L747-E749del, A750P) EGFR(L747-S752del, P753S) EGFR(L747-T751del,Sins)
EGFR(L858R) EGFR(L858R,T790M) EGFR(L861Q) EGFR(S752-I759del) EGFR(T790M)
EGFR/EGFR EGFR/ErbB2 EIF2AK1 EPHA1 EPHA2
EPHA3 EphA4 EphA5 EPHA6 EphA7
EPHA8 EphB1 EphB2 EphB3 EphB4
EPHB6 ErbB1 ERBB2 ErbB2/ErbB3 ErbB2/ErbB4
ErbB2-ErbB3 ERBB3 ErbB4 ErbB4/ErbB4 ERK1
ERK1(Q122L) ERK2 ERK3 ERK4 ERK5
ERK8 ERN1 FAK FER FES
FGFR1 FGFR1-α-Klotho FGFR1-β-Klotho FGFR2 FGFR2(N550K)
FGFR3 FGFR3(G380R)/FGFR3(G380R) FGFR3(G697C) FGFR3(K650E) FGFR3(V555M)
FGFR3/FGFR3 FGFR4 FGFR4 FGFR4-α-Klotho FGFR4-β-Klotho
FGR FLT1 FLT3 FLT3(D835H) FLT3(D835V)
FLT3(D835Y) FLT3(ITD) FLT3(ITD,D835V) FLT3(ITD,F691L) FLT3(K663Q)
FLT3(N841I) FLT3(R834Q) FLT3-autoinhibited FLT4 FRK
FYN GAK GCN2(Kin.Dom.2,S808G) GHR-JAK1 GHR-JAK2
GRK1 GRK2 GRK3 GRK4 GRK7
GSK3A GSK3B HASPIN HCK HIPK1
HIPK2 HIPK3 HIPK4 HPK1 HUNK
ICK IGF1R IKK-alpha IKK-beta IKK-epsilon
INSR INSRa INSRb INSRR IRAK1
IRAK2 IRAK3 IRAK4 ITK JAK1(JH1domain-catalytic)
JAK1(JH2domain-pseudokinase) JAK2(JH1domain-catalytic) JAK3 JAK3(JH1domain-catalytic) JNK1
JNK2 JNK3 KDR KDR/KDR KIT
KIT(A829P) KIT(D816H) KIT(D816V) KIT(L576P) KIT(V559D)
KIT(V559D,T670I) KIT(V559D,V654A) KIT-autoinhibited LATS1 LATS2
LCK LIMK1 LIMK2 LKB1 LOK
LRRK2 LRRK2(G2019S) LTK LYN LZK
MAK MAP3K1 MAP3K15 MAP3K2 MAP3K3
MAP3K4 MAP4K2 MAP4K3 MAP4K4 MAP4K5
MAPKAPK2 MAPKAPK5 MARK1 MARK2 MARK3
MARK4 MAST1 MEK1 MEK2 MEK3
MEK4 MEK5 MEK6 MELK MERTK
MET MET(M1250T) MET(Y1235D) MINK mINSRa
mINSRb MKK7 MKNK1 MKNK2 MLCK
MLK1 MLK2 MLK3 MLKL MLKL(full-length)
MRCKA MRCKB MST1 MST1R MST2
MST3 MST4 MTOR MUSK MYLK
MYLK2 MYLK4 MYO3A MYO3B NDR1
NDR2 NEK1 NEK10 NEK11 NEK2
NEK3 NEK4 NEK5 NEK6 NEK7
NEK9 NIM1 NLK OSR1 p38-alpha
p38-beta p38-delta p38-gamma PAK1 PAK2
PAK3 PAK4 PAK6 PAK7 PASK
PCTK1 PCTK2 PCTK3 PDGFRa PDGFRb
PDPK1 PFCDPK1(P.falciparum) PFPK5(P.falciparum) PFTAIRE2 PFTK1
PHKG1 PHKG2 PI3Kδ PIK3C2B PIK3C2G
PIK3CA PIK3CA(C420R) PIK3CA(E542K) PIK3CA(E545A) PIK3CA(E545K)
PIK3CA(H1047L) PIK3CA(H1047Y) PIK3CA(I800L) PIK3CA(M1043I) PIK3CA(Q546K)
PIK3CB PIK3CD PIK3CG PIK4CB PIKFYVE
PIM1 PIM2 PIM3 PIP5K1A PIP5K1C
PIP5K2B PIP5K2C PKAC-alpha PKAC-alpha(L206R) PKAC-beta
PKMYT1 PKN1 PKN2 PKNB(M.tuberculosis) PLK1
PLK2 PLK3 PLK4 PRKCD PRKCE
PRKCH PRKCI PRKCQ PRKD1 PRKD2
PRKD3 PRKG1 PRKG2 PRKR PRKX
PRLR-JAK1 PRLR-JAK2 PRP4 PYK2 QSK
RAF1 RET RET(A883F) RET(M918T) RET(V804E)
RET(V804L) RET(V804M) rhTrkA-rhP75 RIOK1 RIOK2
RIOK3 RIPK1 RIPK1 RIPK2 RIPK3
RIPK3 RIPK4 RIPK5 ROCK1 ROCK2
ROS1 RPS6KA4(Kin.Dom.1-N-terminal) RPS6KA4(Kin.Dom.2-C-terminal) RPS6KA5(Kin.Dom.1-N-terminal) RPS6KA5(Kin.Dom.2-C-terminal)
RSK1(Kin.Dom.1-N-terminal) RSK1(Kin.Dom.2-C-terminal) RSK2(Kin.Dom.1-N-terminal) RSK2(Kin.Dom.2-C-terminal) RSK3(Kin.Dom.1-N-terminal)
RSK3(Kin.Dom.2-C-terminal) RSK4(Kin.Dom.1-N-terminal) RSK4(Kin.Dom.2-C-terminal) rTrkA-rP75 S6K1
SBK1 SGK SgK110 SGK2 SGK3
SIK SIK1 SIK2 SLK SNARK
SNRK SRC SRMS SRPK1 SRPK2
SRPK3 STK16 STK33 STK35 STK36
STK39 SYK TAK1 TAOK1 TAOK2
TAOK3 TBK1 TEC TESK1 TGFBR1
TGFBR1/ACVR2 TGFBR1/ACVR2B TGFBR1/TGFBR2 TGFBR2 TIE1
TIE2 Tie2 TLK1 TLK2 TNIK
TNK1 TNK2 TNNI3K TrkA TrkA-P75
TrkB TrkB-P75 TrkC TrkC-P75 TRPM6
TSSK1B TSSK3 TTK TXK TYK2
TYK2(JH1domain-catalytic) TYK2(JH2domain-pseudokinase) TYRO3 ULK1 ULK2
ULK3 VEGFR2 VPS34 VRK2 WEE1
WEE2 WNK1 WNK2 WNK3 WNK4
YANK1 YANK2 YANK3 YES YES1
YSK1 YSK4 ZAK ZAP70