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Kinase Targets by Technology

AAK1 ABL1 ABL1(E255K)-phosphorylated ABL1(F317I)-nonphosphorylated ABL1(F317I)-phosphorylated
ABL1(F317L)-nonphosphorylated ABL1(F317L)-phosphorylated ABL1(H396P)-nonphosphorylated ABL1(H396P)-phosphorylated ABL1(M351T)-phosphorylated
ABL1(Q252H)-nonphosphorylated ABL1(Q252H)-phosphorylated ABL1(T315I)-nonphosphorylated ABL1(T315I)-phosphorylated ABL1(Y253F)-phosphorylated
ABL1-nonphosphorylated ABL1-phosphorylated ABL2 ACVR1 ACVR1B
ACVR1B/BMPR2 ACVR1C/ACVR2 ACVR1C/ACVR2B ACVR2/ACVR1 ACVR2A
ACVR2B ACVRL1 ACVRL1/ACVR2 ACVRL1/ACVR2B ACVRL1/BMPR2
ADCK3 ADCK4 AKT1 AKT2 AKT3
ALK ALK(1151Tins) ALK(C1156Y) ALK(F1174L) ALK(L1196M)
AMPK-alpha1 AMPK-alpha2 ANKK1 ARK5 ASK1
ASK2 AURKA AURKB AURKC AXL
BIKE BLK BMPR1A BMPR1A/ACVR2 BMPR1A/ACVR2B
BMPR1A/BMPR2 BMPR1B BMPR1B/ACVR2 BMPR1B/ACVR2B BMPR1B/BMPR2
BMPR2 BMX BRAF BRAF(V600E) BRK
BRSK1 BRSK2 BTK BUB1 CAMK1
CAMK1B CAMK1D CAMK1G CAMK2A CAMK2B
CAMK2D CAMK2G CAMK4 CAMKK1 CAMKK2
CASK CDC2L1 CDC2L2 CDC2L5 CDK1
CDK10 CDK11 CDK12 CDK2 CDK20
CDK3 CDK4 CDK4-cyclinD1 CDK4-cyclinD1(F93L) CDK4-cyclinD3
CDK5 CDK6 CDK7 CDK8 CDK9
CDKL1 CDKL2 CDKL3 CDKL5 CHEK1
CHEK2 cINSRa cINSRb CIT c-KIT
CLK1 CLK2 CLK3 CLK4 c-MET/c-MET
c-Ret-GFRα1 c-Ret-GFRα2 CSF1R CSF1R/CSF1R CSF1R-autoinhibited
CSF3R-JAK1 CSK CSNK1A1 CSNK1A1L CSNK1D
CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 CSNK2A1
CSNK2A2 CTK DAPK1 DAPK2 DAPK3
DCAMKL1 DCAMKL2 DCAMKL3 DDR1 DDR2(T654M)
DLK DMPK DMPK2 DRAK1 DRAK2
DYRK1A DYRK1B DYRK2 EGFR EGFR(E746-A750del)
EGFR(G719C) EGFR(G719S) EGFR(L747-E749del, A750P) EGFR(L747-S752del, P753S) EGFR(L747-T751del,Sins)
EGFR(L858R) EGFR(L858R,T790M) EGFR(L861Q) EGFR(S752-I759del) EGFR(T790M)
EGFR/EGFR EGFR/ErbB2 EGFR/ErbB3 EIF2AK1 EPHA1
EPHA2 EPHA3 EphA4 EphA5 EPHA6
EphA7 EPHA8 EphB1 EphB2 EphB3
EphB4 EPHB6 ErbB1 ERBB2 ErbB2/ErbB3
ErbB2/ErbB4 ErbB2-ErbB3 ERBB3 ErbB4 ErbB4/ErbB4
ERK1 ERK1(Q122L) ERK2 ERK3 ERK4
ERK5 ERK8 ERN1 FAK FER
FES FGFR1 FGFR1-α-Klotho FGFR1-β-Klotho FGFR2
FGFR2(N550K) FGFR3 FGFR3(G380R)/FGFR3(G380R) FGFR3(G697C) FGFR3(K650E)
FGFR3(V555M) FGFR3/FGFR3 FGFR4 FGFR4 FGFR4-α-Klotho
FGFR4-β-Klotho FGR FLT1 FLT3 FLT3(D835H)
FLT3(D835V) FLT3(D835Y) FLT3(ITD) FLT3(ITD,D835V) FLT3(ITD,F691L)
FLT3(K663Q) FLT3(N841I) FLT3(R834Q) FLT3-autoinhibited FLT4
FRK FYN GAK GCN2(Kin.Dom.2,S808G) GHR-JAK1
GHR-JAK2 GRK1 GRK2 GRK3 GRK4
GRK7 GSK3A GSK3B HASPIN HCK
HIPK1 HIPK2 HIPK3 HIPK4 HPK1
HUNK ICK IGF1R IKK-alpha IKK-beta
IKK-epsilon INSR INSRa INSRb INSRR
IRAK1 IRAK2 IRAK3 IRAK4 ITK
JAK1(JH1domain-catalytic) JAK1(JH2domain-pseudokinase) JAK2(JH1domain-catalytic) JAK3 JAK3(JH1domain-catalytic)
JNK1 JNK2 JNK3 KDR KDR/KDR
KIT KIT(A829P) KIT(D816H) KIT(D816V) KIT(L576P)
KIT(V559D) KIT(V559D,T670I) KIT(V559D,V654A) KIT-autoinhibited LATS1
LATS2 LCK LIMK1 LIMK2 LKB1
LOK LRRK2 LRRK2(G2019S) LTK LYN
LZK MAK MAP3K1 MAP3K15 MAP3K2
MAP3K3 MAP3K4 MAP4K2 MAP4K3 MAP4K4
MAP4K5 MAPKAPK2 MAPKAPK5 MARK1 MARK2
MARK3 MARK4 MAST1 MEK1 MEK2
MEK3 MEK4 MEK5 MEK6 MELK
MERTK MET MET(M1250T) MET(Y1235D) MINK
mINSRa mINSRb MKK7 MKNK1 MKNK2
MLCK MLK1 MLK2 MLK3 MLKL
MLKL(full-length) MRCKA MRCKB MST1 MST1R
MST2 MST3 MST4 MTOR MUSK
MYLK MYLK2 MYLK4 MYO3A MYO3B
NDR1 NDR2 NEK1 NEK10 NEK11
NEK2 NEK3 NEK4 NEK5 NEK6
NEK7 NEK9 NIM1 NLK OSR1
p38-alpha p38-beta p38-delta p38-gamma PAK1
PAK2 PAK3 PAK4 PAK6 PAK7
PASK PCTK1 PCTK2 PCTK3 PDGFRa
PDGFRb PDPK1 PFCDPK1(P.falciparum) PFPK5(P.falciparum) PFTAIRE2
PFTK1 PHKG1 PHKG2 PI3Kδ PIK3C2B
PIK3C2G PIK3CA PIK3CA(C420R) PIK3CA(E542K) PIK3CA(E545A)
PIK3CA(E545K) PIK3CA(H1047L) PIK3CA(H1047Y) PIK3CA(I800L) PIK3CA(M1043I)
PIK3CA(Q546K) PIK3CB PIK3CD PIK3CG PIK4CB
PIKFYVE PIM1 PIM2 PIM3 PIP5K1A
PIP5K1C PIP5K2B PIP5K2C PKAC-alpha PKAC-alpha(L206R)
PKAC-beta PKMYT1 PKN1 PKN2 PKNB(M.tuberculosis)
PLK1 PLK2 PLK3 PLK4 PRKCD
PRKCE PRKCH PRKCI PRKCQ PRKD1
PRKD2 PRKD3 PRKG1 PRKG2 PRKR
PRKX PRLR-JAK1 PRLR-JAK2 PRP4 PYK2
QSK RAF1 RET RET(A883F) RET(M918T)
RET(V804E) RET(V804L) RET(V804M) rhTrkA-rhP75 RIOK1
RIOK2 RIOK3 RIPK1 RIPK1 RIPK2
RIPK3 RIPK3 RIPK4 RIPK5 ROCK1
ROCK2 ROS1 RPS6KA4(Kin.Dom.1-N-terminal) RPS6KA4(Kin.Dom.2-C-terminal) RPS6KA5(Kin.Dom.1-N-terminal)
RPS6KA5(Kin.Dom.2-C-terminal) RSK1(Kin.Dom.1-N-terminal) RSK1(Kin.Dom.2-C-terminal) RSK2(Kin.Dom.1-N-terminal) RSK2(Kin.Dom.2-C-terminal)
RSK3(Kin.Dom.1-N-terminal) RSK3(Kin.Dom.2-C-terminal) RSK4(Kin.Dom.1-N-terminal) RSK4(Kin.Dom.2-C-terminal) rTrkA-rP75
S6K1 SBK1 SGK SgK110 SGK2
SGK3 SIK SIK1 SIK2 SLK
SNARK SNRK SRC SRMS SRPK1
SRPK2 SRPK3 STK16 STK33 STK35
STK36 STK39 SYK TAK1 TAOK1
TAOK2 TAOK3 TBK1 TEC TESK1
TGFBR1 TGFBR1/ACVR2 TGFBR1/ACVR2B TGFBR1/TGFBR2 TGFBR1/TGFBR2/ENG
TGFBR2 TIE1 TIE2 Tie2 TLK1
TLK2 TNIK TNK1 TNK2 TNNI3K
TrkA TrkA-P75 TrkB TrkB-P75 TrkC
TrkC-P75 TRPM6 TSSK1B TSSK3 TTK
TXK TYK2 TYK2(JH1domain-catalytic) TYK2(JH2domain-pseudokinase) TYRO3
ULK1 ULK2 ULK3 VEGFR2 VPS34
VRK2 WEE1 WEE2 WNK1 WNK2
WNK3 WNK4 YANK1 YANK2 YANK3
YES YES1 YSK1 YSK4 ZAK
ZAP70