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Investigate Kinase Targets

World’s Largest Portfolio of Kinase Assays

DiscoverX offers the most comprehensive menu of in vitro biochemical and cell-based assays for evaluating kinase activity. Our in vitro biochemical kinase panel includes an industry-leading set of > 460 assays, allowing rapid and efficient determination of kinome-wide potency and selectivity of compounds. By integrating EFC technology, kinase knowledge, and expertise in cell-based assays, we also offer a growing menu of homogenous, functional assays to detect activated kinases in whole cells. Used alone or in combination, these powerful assay platforms can be used at all stages of drug discovery and are ideal for identifying highly potent and selective kinase inhibitors.

Learn more about the updated Cell Culture and Handling Procedure in the new Technical Bulletin.

CDC-like Kinase
Extracellular signal-regulated kinase
Non-receptor tyrosine kinase
Phosphoinositide kinase
Protein Kinase
Protein Tyrosine Kinase
Explore our KINOMEscan Assay Panel

Cell Lines

Explore our growing panel of target-specific, stable kinase cell lines for measuring the activity of receptor tyrosine kinases (RTKs) and non-receptor cytosolic tyrosine kinases (CTKs) as well as binding to internal kinases.
Learn how InCELL Compound-Target Engagement works >
Learn how PathHunter Kinase assays work >

Assay Ready Kits

Assay Ready products are complete, ready-to-use kits that include all the cells and reagents to measure kinase activation or binding in live cells. Free yourself from lengthy cell culture and expensive instrumentation.
Learn about Assay Ready eXpress™ Kits >

Biochemical Assays

Study active kinases using our universal ADP accumulation assays. Explore inactive and active kinases with one of our highly quantitative, competitive binding platforms without using antibodies or kinase substrates.
Learn about ADP Accumulation assays >

Cell Culture Kits, Reagents & Consumables

Performance you can trust! Get the highest quality data from your cell-based kinase assays in combination with our lab-certified PathHunter® cell culture media, tissue culture reagents and plates.

Ligands & Inhibitors

Designed to target a specific kinase receptor or pathway, our purified reference ligands and inhibitors are a convenient and cost-effective way to validate any stable Kinase cell line or assay-ready kit.
View reference compound data >

Detection Reagents

Get optimal assay performance using certified chemiluminescent or fluorescent PathHunter® and InCELL Detection Reagents that have been validated for use in both 96-well and 384-well microplate formats
How detection works >