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forkhead box O3 (forkhead box O3)

Target Class
Pathway
Family
Pathway
Official Symbol
FOXO3
Species
Human
Accession Number
NM_001455
Alias Names
AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A; forkhead box O3; forkhead box O3A; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
Background
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members:

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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Measures Background Species Cell Line
FOXO3 Translocation U2OS Human 93-0876C3
Assay Measures Background Species Assay Kit
PDT/AKT Inhibition U2OS Human 93-0876E3CP5S
PDT/AKT Inhibition U2OS Human 93-0876E3CP5M
PDT/AKT Inhibition U2OS Human 93-0876E3CP5L

KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
          Available