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Cell division cycle 25 homolog A (CDC25A)

Target Class
Pathway
Family
Cell Cycle Protein
Official Symbol
CDC25A
Species
Human
Accession Number
NM_001789.2
Alias Names
CDC25A2; CDC25A2-CAG isoform; M-phase inducer phosphatase 1; cell division cycle 25 homolog A (S. cerevisiae); cell division cycle 25 homolog A (S. pombe); cell division cycle 25A; dual specificity phosphatase CDC25A
Background
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Solution Portfolio

Related Group Members:

Cell Cycle Protein
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family

Assay Measures Background Species Cell Line
CDC25A Degradation U2OS Human 93-0765C3
Cdc25a Degradation NCI-H460 Human 93-0776C12
Assay Measures Background Species Assay Kit
CDC25A Degradation U2OS Human 93-0765E3CP0S
CDC25A Degradation U2OS Human 93-0765E3CP0M
CDC25A Degradation U2OS Human 93-0765E3CP0L

KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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