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Spleen tyrosine kinase (SYK)

Target Class
Kinase
Family
Cytosolic tyrosine kinase
Official Symbol
SYK
Species
Human
Accession Number
NM_003177.5
Alias Names
p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK
Background
This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
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Solution Portfolio

Related Group Members: Cytosolic tyrosine kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Measures Background Species Cell Line
Receptor Phosphorylation U2OS Human 93-0865C3
Assay Measures Background Species Assay Kit
Receptor Phosphorylation U2OS Human 93-0865E3CP16S
Receptor Phosphorylation U2OS Human 93-0865E3CP16M
Receptor Phosphorylation U2OS Human 93-0865E3CP16L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available Available