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salt-inducible kinase 2 (SIK2)

Target Class
Kinase
Family
CAMK
Official Symbol
SIK2
Entrez Gene ID
23235
Species
Human
Accession Number
NP_056006.1
Alias Names
LOH11CR1I; QIK; SIK-2; SNF1-like kinase 2; SNF1LK2; qin-induced kinase; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; serine/threonine-protein kinase SNF1-like kinase 2
Background
Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
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Solution Portfolio

Related Group Members: CAMK
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available