Targets / Kinase / RPS6KA4(Kin.Dom.1-N-terminal)

ribosomal protein S6 kinase, 90kDa, polypeptide 4 (RPS6KA4(Kin.Dom.1-N-terminal))

Target Class
Kinase
Family
AGC
Official Symbol
RPS6KA4
Entrez Gene ID
8986
Species
Human
Accession Number
NP_001006945.1
Alias Names
90 kDa ribosomal protein S6 kinase 4; MSK2; RSK-B; RSKB; S6K-alpha-4; mitogen- and stress-activated protein kinase 2; nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein S6 kinase alpha 4; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; ribosomal protein kinase B
Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
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Related Group Members: AGC
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