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Rho-associated, coiled-coil containing protein kinase 2 (ROCK2)

Target Class
Kinase
Family
AGC
Official Symbol
ROCK2
Entrez Gene ID
9475
Species
Human
Accession Number
NP_004841.2
Alias Names
ROCK-II; Rho-associated, coiled-coil containing protein kinase 2; p164 ROCK-2; rho-associated protein kinase 2; rho-associated, coiled-coil-containing protein kinase II
Background
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]
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Related Group Members: AGC
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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