Biological Information | |
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Background Information: | The RET (rearranged during transfection) receptor tyrosine kinase is a classic example of phenotype heterogeneity. Gain-of-function mutations of RET are associated with human cancer and multiple endocrine neoplasia type 2 (MEN 2A, MEN 2B, etc.) Loss-of-function mutations of RET cause Hirschspung disease or colonic aganglionosis).
GenBank NM_000323 |
Target Class: | Kinase |
Accession Number: | NM_020630.4; NM_020975.4 |
Target Name: | Ret |
Target Aliases: | RET, HSCR1, MEN2A, PTC, CDHF12, RET51, RET-ELE1, C-ret, MTC1, MEN2B |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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