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myosin light chain kinase 3 (MLCK)

Target Class
Kinase
Family
CAMK
Official Symbol
MYLK3
Entrez Gene ID
91807
Species
Human
Accession Number
NP_872299.2
Alias Names
MLC kinase; MLCK; MLCK2; caMLCK; cardiac-MyBP-C associated Ca/CaM kinase; cardiac-MyBP-C-associated Ca/CaM kinase; myosin light chain kinase 3; putative myosin light chain kinase 3
Background
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]
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Related Group Members: CAMK
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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