Targets / Kinase / IRAK1

Interleukin-1 receptor-associated kinase 1 (IRAK1)

Target Class
Kinase
Family
TKL
Official Symbol
IRAK1
Entrez Gene ID
3654
Species
Human
Accession Number
NP_001560.2
Alias Names
IRAK; IRAK-1; Pelle homolog; interleukin-1 receptor-associated kinase 1; pelle
Background
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Related Group Members: TKL
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