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interleukin-1 receptor-associated kinase 1 (IRAK1)

Target Class
Kinase
Family
TKL
Official Symbol
IRAK1
Entrez Gene ID
3654
Species
Human
Accession Number
NP_001560.2
Alias Names
IRAK; IRAK-1; Pelle homolog; interleukin-1 receptor-associated kinase 1; pelle
Background
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Related Group Members: TKL
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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