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insulin receptor (INSR)

Target Class
Kinase
Family
TK
Official Symbol
INSR
Entrez Gene ID
3643
Species
Human
Accession Number
NP_000199.2
Alias Names
CD220; HHF5; IR; insulin receptor
Background
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Related Group Members: TK
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KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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